The name Sandrina is best understood as a variant, modern spelling, compound, or stylistic form connected to Sandra. The root name Sandra has origins in Greek via Alexandra and is generally associated with the meaning defender of mankind. This gives Sandrina a connection to the sound and symbolism of Sandra, while allowing for a more distinctive or contemporary spelling. Because Sandrina itself may not have a separate ancient etymology, its meaning is most safely traced through the better-documented root name Sandra.

The root form of Sandrina is Sandrina — meaning "Graceful defender of mankind.".

Sandrina remains a beloved choice, ranking #13 in the US. Timeless appeal across cultures and generations.