The surname Comer has multiple origins and meanings. It can be derived from the Old English word cumb meaning valley, indicating that the name was given to those who lived near a valley. Alternatively, it could be derived from the Gaelic word comar, meaning confluence, referring to someone who lived near a meeting point of two bodies of water. Comer is an occupational surname associated with the Middle English word comer, meaning merchant. This suggests that it could have been given to traders or businessmen during the medieval era. Notable individuals with the surname Comer include Jerry Comer, a former American football player, and Grace Comer Reed, a prominent American educator. The name has gained popularity as a first name in recent years, signifying that it has transcended its original meaning as a surname to become a given name.

The root form of Comer is Comer — meaning "Consumer" or "one who eats.".

Comer remains a beloved choice, ranking #14 in the US. Timeless appeal across cultures and generations.