The name Marylene is best understood as a variant, modern spelling, compound, or stylistic form connected to Maria. The root name Maria has origins in Latin and Hebrew tradition and is generally associated with the meaning beloved, bitter, or wished-for child depending on interpretation. This gives Marylene a connection to the sound and symbolism of Maria, while allowing for a more distinctive or contemporary spelling. Because Marylene itself may not have a separate ancient etymology, its meaning is most safely traced through the better-documented root name Maria.

The root form of Marylene is Marylene — meaning "Marylene" means "bitter or rebellious".

Marylene remains a beloved choice, ranking #6 in the US. Timeless appeal across cultures and generations.